Mouse Hecw2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hecw2
Locus ID	329152
Kit Components	GA216719G1, Hecw2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216719G2, Hecw2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216719G3, Hecw2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001001883, NM_172655
Synonyms	A730039N16Rik; D030049F17Rik; Gm971; mKIAA1301; Nedl2
Summary	E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Involved in the regulation of mitotic metaphase/anaphase transition.[UniProtKB/Swiss-Prot Function]

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