CDK5 Human Gene Knockout Kit (CRISPR)
CAT#: KN200342LP
CDK5 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
CNY 3,710.00
CNY 1,999.00
CNY 2,700.00
CNY 3,600.00
CNY 4,465.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | CDK5 |
Locus ID | 1020 |
Kit Components |
KN200342G1, CDK5 gRNA vector 1 in pCas-Guide CRISPR vector KN200342G2, CDK5 gRNA vector 2 in pCas-Guide CRISPR vector KN200342LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001164410, NM_004935 |
Synonyms | PSSALRE |
Summary | This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN200342 | CDK5 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN200342BN | CDK5 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN200342RB | CDK5 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN400342 | CDK5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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GA100733 | CDK5 CRISPRa kit - CRISPR gene activation of human cyclin dependent kinase 5 |
CNY 12,255.00 |