Monocarboxylic acid transporter 1 (SLC16A1) Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA	mBFP-Neo
Symbol	Monocarboxylic acid transporter 1
Locus ID	6566
Kit Components	KN205213G1, Monocarboxylic acid transporter 1 gRNA vector 1 in pCas-Guide CRISPR vector KN205213G2, Monocarboxylic acid transporter 1 gRNA vector 2 in pCas-Guide CRISPR vector KN205213BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001166496, NM_003051
Synonyms	HHF7; MCT; MCT1; MCT1D
Summary	The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009]

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