RO60 Human Gene Knockout Kit (CRISPR)

CAT#: KN206071BN

TROVE2 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


RO60 rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TROVE2 (Myc-DDK-tagged)-Human TROVE domain family, member 2 (TROVE2), transcript variant 3
    • 10 ug

CNY 4,016.00
CNY 4,560.00

Specifications

Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol RO60
Locus ID 6738
Kit Components

KN206071G1, RO60 gRNA vector 1 in pCas-Guide CRISPR vector

KN206071G2, RO60 gRNA vector 2 in pCas-Guide CRISPR vector

KN206071BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001042369, NM_001042370, NM_001173524, NM_001173525, NM_004600, NR_033393, NM_001331020
Synonyms RO60; RORNP; SSA2
Summary RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation (PubMed:18056422). Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammaotry cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes (PubMed:26382853).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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