NEI3 (NEIL3) Human Gene Knockout Kit (CRISPR)

CAT#: KN206838LP

NEIL3 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Rabbit polyclonal anti-NEIL3 antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


NEIL3 (Myc-DDK-tagged)-Human nei endonuclease VIII-like 3 (E. coli) (NEIL3)
    • 10 ug

CNY 4,504.00
CNY 4,560.00

Specifications

Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol NEI3
Locus ID 55247
Kit Components

KN206838G1, NEI3 gRNA vector 1 in pCas-Guide CRISPR vector

KN206838G2, NEI3 gRNA vector 2 in pCas-Guide CRISPR vector

KN206838LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_018248
Synonyms FGP2; FPG2; hFPG2; hNEI3; NEI3; ZGRF3
Summary NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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