beta 2 Microglobulin (B2M) Human Gene Knockout Kit (CRISPR)

CAT#: KN207587BN

B2M - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


B2M mouse monoclonal antibody,clone 1A9, Magnetic Beads
    • 1 ml

CNY 7,700.00


B2M (untagged)-Human beta-2-microglobulin (B2M)
    • 10 ug

CNY 1,200.00
CNY 2,950.00

Specifications

Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol beta 2 Microglobulin
Locus ID 567
Kit Components

KN207587G1, beta 2 Microglobulin gRNA vector 1 in pCas-Guide CRISPR vector

KN207587G2, beta 2 Microglobulin gRNA vector 2 in pCas-Guide CRISPR vector

KN207587BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004048
Synonyms IMD43
Summary This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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