Heparanase 1 (HPSE) Human Gene Knockout Kit (CRISPR)

CAT#: KN208556LP

HPSE - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

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CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
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HPSE (Myc-DDK-tagged)-Human heparanase (HPSE), transcript variant 1
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Specifications

Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol Heparanase 1
Locus ID 10855
Kit Components

KN208556G1, Heparanase 1 gRNA vector 1 in pCas-Guide CRISPR vector

KN208556G2, Heparanase 1 gRNA vector 2 in pCas-Guide CRISPR vector

KN208556LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001098540, NM_001166498, NM_001199830, NM_006665
Synonyms HPA; HPA1; HPR1; HPSE1; HSE1
Summary Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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