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Zinc transporter 8 (SLC30A8) Human Gene Knockout Kit (CRISPR)
CAT＃: KN220964LP
SLC30A8 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
Product images
CNY 3,710.00
CNY 5,488.00
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
| Donor DNA | Luciferase-Puro |
| Symbol | Zinc transporter 8 |
| Locus ID | 169026 |
| Kit Components |
KN220964G1, Zinc transporter 8 gRNA vector 1 in pCas-Guide CRISPR vector KN220964G2, Zinc transporter 8 gRNA vector 2 in pCas-Guide CRISPR vector KN220964LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. pUC vector backbone in gray; Left arm sequence in blue; Luciferase-Puro in green; Right arm in violet AAGGCGAGTT ACATGATCCC CCATGTTGTG CAAAAAAGCG GTTAGCTCCT TCGGTCCTCC GATCGTTGTC AGAAGTAAGT TGGCCGCAGT GTTATCACTC ATGGTTATGG CAGCACTGCA TAATTCTCTT ACTGTCATGC CATCCGTAAG ATGCTTTTCT GTGACTGGTG AGTACTCAAC CAAGTCATTC TGAGAATAGT GTATGCGGCG ACCGAGTTGC TCTTGCCCGG CGTCAATACG GGATAATACC GCGCCACATA GCAGAACTTT AAAAGTGCTC ATCATTGGAA AACGTTCTTC GGGGCGAAAA CTCTCAAGGA TCTTACCGCT GTTGAGATCC AGTTCGATGT AACCCACTCG TGCACCCAAC TGATCTTCAG CATCTTTTAC TTTCACCAGC GTTTCTGGGT GAGCAAAAAC AGGAAGGCAA AATGCCGCAA AAAAGGGAAT AAGGGCGACA CGGAAATGTT GAATACTCAT ACTCTTCCTT TTTCAATATT ATTGAAGCAT TTATCAGGGT TATTGTCTCA TGAGCGGATA CATATTTGAA TGTATTTAGA AAAATAAACA AATAGGGGTT CCGCGCACAT TTCCCCGAAA AGTGCCACCT GACGTCTAAG AAACCATTAT TATCATGACA TTAACCTATA AAAATAGGCG TATCACGAGG CCCTTTCGGG TCGCGCGTTT CGGTGATGAC GGTGAAAACC TCTGACACAT GCAGCTCCCG TTGACGGTCA CAGCTTGTCT GTAAGCGGAT GCCGGGAGCA GACAAGCCCG TCAGGGCGCG TCAGCGGGTG TTGGCGGGTG TCGGGGCTGG CTTAACTATG CGGCATCAGA GCAGATTGTA CTGAGAGTGC ACCATAAAAT TGTAAACGTT AATATTTTGT TAAAATTCGC GTTAAATTTT TGTTAAATCA GCTCATTTTT TAACCAATAG GCCGAAATCG GCAAAATCCC TTATAAATCA AAAGAATAGC CCGAGATAGG GTTGAGTGTT GTTCCAGTTT GGAACAAGAG TCCACTATTA AAGAACGTGG ACTCCAACGT CAAAGGGCGA AAAACCGTCT ATCAGGGCGA TGGCCCACTA CGTGAACCAT CACCCAAATC AAGTTTTTTG GGGTCGAGGT GCCGTAAAGC ACTAAATCGG AACCCTAAAG GGAGCCCCCG ATTTAGAGCT TGACGGGGAA AGCCGGCGAA CGTGGCGAGA AAGGAAGGGA AGAAAGCGAA AGGAGCGGGC GCTAGGGCGC TGGCAAGTGT AGCGGTCACG CTGCGCGTAA CCACCACACC CGCCGCGCTT AATGCGCCGC TACAGGGCGC GTACTATGGT TGCTTTGACG TATGCGGTGT GAAATACCGC ACAGATGCGT AAGGAGAAAA TACCGCATCA GGCGCCATTC GCCATTCAGG CTGCGCAACT GTTGGGAAGG GCGATCGGTG CGGGCCTCTT CGCTATTACG CCAGCTGGCG AAAGGGGGAT GTGCTGCAAG GCGATTAAGT TGGGTAACGC CAGGGTTTTC CCAGTCACGA CGTTGTAAAA CGACGGCCAG TGAATTGGAG GCTACAGTCA GTGGAGAGGA CTTTCACAGG CTGTCGCCGT GCTCATTTGA TAACTGCCCG TTATTCATGC GACACACTGG TTTCAGAAAC TATTGACCCT TGTCCTCCCT TTCAATAGTG AAATCCCAAA ATGGTCCTAG GAGAGACAAG TAAATTCTGA CAGCTGCTTA GAGGTCATCT TAGAACTAAA TTCCAAAGAA ATAATTTTAG GCTGATAAAG AGTCCAGAAA AAGGAGGAGG GAGAGAAAAA GAAAGAATTA GTTTAGTGTA GCGAATGGTA GCTATTTGCA GCTCACCCAC GTGTGCTCCG AAGGTCAAAA CCCTACATCA GCAATTTGTA GCAAGCTCTT GAGCTCCTCT ACCTCTTAGA AAGCACAATT GAATCAGATA TCATATGAAA GACATACACA CTTCATGTAA TGCTACCTGC AAGTCTCCCT AGAAAAGCAG TTTTTGTAGG TGAAAACAAT GAAGCCAGGT AATATTGCAA GGAGGCTGTA ATTTTAGCAG ACCTACCAAC AACACTGATG TAGGAAGCTC ATTATTTTAA TTTCTGGAGC CTTTTAATTT TTTCTTTAGA AAGTGTATAA ATAATTGCAG TGCTGCTTTG CTTCCAAAAC TGGGCAGTGA GTTCAACAAC AACGACAACA ACAGCCGCAG CTCATCCTGG CCGTCGTTGC TTCTGAATTG TAGGCCTTTA CTCTGCAACT TGGGGGCACT CTGGAACATT TTATAAGTTG TTGACTGACA TGTATTTTAT ATTCTGAAAA ATGCAATACT TTATATAGTT GATTTGATTC CTTAAATATC CTAAGTGCAT AAAGAACACA TTTTACTGAT GTGTTTTTCA TCTGTCATGT TTATTCCAGA AAATAGACCT ATATAATCTG TTTACTTTTC CTTTTCTCAA TTATTCTCAA TTTTAAGATA GATAGTAAAT TTTATTATAT TATATTTAGA AAAAGTTAAG ACTTCAGCTA CATGGCAAAA TTGTGGTTGT ATTGATCTTA AAATGAGCTG TTGTTTTCAT GCTTATAAAG TATCATTATT AATATACATA CCTATAACAA ATATAGCTGA TTTTAATGTT CTACAAAGTA TTCCATTTCT TTTTAATGTC TCCCACAGTG TCACATGCAA TACATTCATT CATTTTTCAC TTGGTTAACA ATTATTGATT GAACACACCT GTAGTAAGTG CAGAACTTAT AATGAGAAAG AAAAAAATGT CTAGTTTCAG ATCTTTGTCC TCTTGAAACT TAGTCTAATG TGAAATCACT CTCGCCGGTT GGACTTTAGA TCAGAAGGGA TCTTGCTGCC GCCCGAAAGA GGAAGGGCTG GAAGAGGAAG GAGCTTGGCG TAATCATGGT CATAGCTGTT TCCTGTGTGA AATTGTTATC CGCTCACAAT TCCACACAAC ATACGAGCCG GAAGCATAAA GTGTAAAGCC TGGGGTGCCT AATGAGTGAG CTAACTCACA TTAATTGCGT TGCGCTCACT GCCCGCTTTC CAGTCGGGAA ACCTGTCGTG CCAGCTGCAT TAATGAATCG GCCAACGCGC GGGGAGAGGC GGTTTGCGTA TTGGGCGCTC TTCCGCTTCC TCGCTCACTG ACTCGCTGCG CTCGGTCGTT CGGCTGCGGC GAGCGGTATC AGCTCACTCA AAGGCGGTAA TACGGTTATC CACAGAATCA GGGGATAACG CAGGAAAGAA CATGTGAGCA AAAGGCCAGC AAAAGGCCAG GAACCGTAAA AAGGCCGCGT TGCTGGCGTT TTTCCATAGG CTCCGCCCCC CTGACGAGCA TCACAAAAAT CGACGCTCAA GTCAGAGGTG GCGAAACCCG ACAGGACTAT AAAGATACCA GGCGTTTCCC CCTGGAAGCT CCCTCGTGCG CTCTCCTGTT CCGACCCTGC CGCTTACCGG ATACCTGTCC GCCTTTCTCC CTTCGGGAAG CGTGGCGCTT TCTCATAGCT CACGCTGTAG GTATCTCAGT TCGGTGTAGG TCGTTCGCTC CAAGCTGGGC TGTGTGCACG AACCCCCCGT TCAGCCCGAC CGCTGCGCCT TATCCGGTAA CTATCGTCTT GAGTCCAACC CGGTAAGACA CGACTTATCG CCACTGGCAG CAGCCACTGG TAACAGGATT AGCAGAGCGA GGTATGTAGG CGGTGCTACA GAGTTCTTGA AGTGGTGGCC TAACTACGGC TACACTAGAA GAACAGTATT TGGTATCTGC GCTCTGCTGA AGCCAGTTAC CTTCGGAAAA AGAGTTGGTA GCTCTTGATC CGGCAAACAA ACCACCGCTG GTAGCGGTGG TTTTTTTGTT TGCAAGCAGC AGATTACGCG CAGAAAAAAA GGATCTCAAG AAGATCCTTT GATCTTTTCT ACGGGGTCTG ACGCTCAGTG GAACGAAAAC TCACGTTAAG GGATTTTGGT CATGAGATTA TCAAAAAGGA TCTTCACCTA GATCCTTTTA AATTAAAAAT GAAGTTTTAA ATCAATCTAA AGTATATATG AGTAAACTTG GTCTGACAGT TACCAATGCT TAATCAGTGA GGCACCTATC TCAGCGATCT GTCTATTTCG TTCATCCATA GTTGCCTGAC TCCCCGTCGT GTAGATAACT ACGATACGGG AGGGCTTACC ATCTGGCCCC AGTGCTGCAA TGATACCGCG AGAACCACGC TCACCGGCTC CAGATTTATC AGCAATAAAC CAGCCAGCCG GAAGGGCCGA GCGCAGAAGT GGTCCTGCAA CTTTATCCGC CTCCATCCAG TCTATTAATT GTTGCCGGGA AGCTAGAGTA AGTAGTTCGC CAGTTAATAG TTTGCGCAAC GTTGTTGCCA TTGCTACAGG CATCGTGGTG TCACGCTCGT CGTTTGGTAT GGCTTCATTC AGCTCCGGTT CCCAACGATCGE100003, scramble sequence in pCas-Guide vector |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001172811, NM_001172813, NM_001172814, NM_001172815, NM_173851 |
| Synonyms | ZnT-8; ZNT8 |
| Summary | The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010] |
Documents
| Product Manuals |
| FAQs |
Resources
| 基因表达相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| KN220964 | SLC30A8 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
| KN220964BN | SLC30A8 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
| KN220964RB | SLC30A8 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
| KN420964 | SLC30A8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
|
| GA116181 | SLC30A8 CRISPRa kit - CRISPR gene activation of human solute carrier family 30 member 8 |
CNY 12,255.00 |
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