Transglutaminase 2 (TGM2) (NM_198951) Human Mass Spec Standard

CAT#: PH300226

TGM2 MS Standard C13 and N15-labeled recombinant protein (NP_945189)



  View other "Transglutaminase 2" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transcript variant 1
    • 100 ug

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Specifications

Product Data
Description TGM2 MS Standard C13 and N15-labeled recombinant protein (NP_945189)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200226
Predicted MW 61.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_945189
RefSeq Size 1879
RefSeq ORF 1644
Synonyms G(h); hTG2; TG(C); TGC; tTG
Locus ID 7052
Cytogenetics 20q11.23
Summary Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Huntington's disease
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