LDOC1 (NM_012317) Human Mass Spec Standard

Specifications

Product Data
Description	LDOC1 MS Standard C13 and N15-labeled recombinant protein (NP_036449)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200543
Predicted MW	17 kDa
Protein Sequence	Sequence Link (showhide) >RC200543 protein sequence Red=Cloning site Green=Tags(s) MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPSCPVPFPETFNGESSRLPEFIVQ TASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQCFGWDDDEDDDDE EEEDDY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_036449
RefSeq Size	1470
RefSeq ORF	438
Synonyms	BCUR1; Mar7; Mart7; RTL7; SIRH7
Locus ID	23641
Cytogenetics	Xq27.1
Summary	The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]

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