VTI1B (NM_006370) Human Mass Spec Standard

Specifications

Product Data
Description	VTI1B MS Standard C13 and N15-labeled recombinant protein (NP_006361)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201172
Predicted MW	26.7 kDa
Protein Sequence	Sequence Link (showhide) >RC201172 protein sequence Red=Cloning site Green=Tags(s) MASSAASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAP LSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLN RATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLS IIILLELAILGGLVYYKFFRSH TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006361
RefSeq Size	1357
RefSeq ORF	696
Synonyms	v-SNARE; VTI1; VTI1-LIKE; vti1-rp1; VTI1L; VTI2
Locus ID	10490
Cytogenetics	14q24.1
Summary	V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	SNARE interactions in vesicular transport

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