GADD45G (NM_006705) Human Mass Spec Standard

Specifications

Product Data
Description	GADD45G MS Standard C13 and N15-labeled recombinant protein (NP_006696)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201364
Predicted MW	17.1 kDa
Protein Sequence	Sequence Link (showhide) >RC201364 protein sequence Red=Cloning site Green=Tags(s) MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFCVLAAGEEDEG DIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPGDLHCILISNPNEDAWKDPALEKLSL FCEESRSVNDWVPSITLPE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006696
RefSeq Size	1087
RefSeq ORF	477
Synonyms	CR6; DDIT2; GADD45gamma; GRP17
Locus ID	10912
Cytogenetics	9q22.2
Summary	This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]
Protein Pathways	Cell cycle, MAPK signaling pathway, p53 signaling pathway

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