Caspase-7 (CASP7) (NM_033339) Human Mass Spec Standard

CAT#: PH302059

CASP7 MS Standard C13 and N15-labeled recombinant protein (NP_203125)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

Cited in 1 publication.

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Specifications

Product Data
Description CASP7 MS Standard C13 and N15-labeled recombinant protein (NP_203125)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202059
Predicted MW 34.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_203125
RefSeq Size 2681
RefSeq ORF 909
Synonyms CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3
Locus ID 840
Cytogenetics 10q25.3
Summary This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Protein Families Druggable Genome, Protease
Protein Pathways Alzheimer's disease, Apoptosis
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