TMS1 (PYCARD) (NM_145183) Human Mass Spec Standard

CAT#: PH302409

PYCARD MS Standard C13 and N15-labeled recombinant protein (NP_660184)



  View other "TMS1" proteins (9)

Need it in bulk or customized?
Get a free quote

CNY 19,520.00


货期*
4周

规格
    • 10 ug

Product images

经常一起买 (2)
Transient overexpression lysate of PYD and CARD domain containing (PYCARD), transcript variant 3
    • 100 ug

CNY 3,080.00


PYCARD (TMS1) mouse monoclonal antibody, clone OTI3E9 (formerly 3E9)
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Description PYCARD MS Standard C13 and N15-labeled recombinant protein (NP_660184)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202409
Predicted MW 15 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_660184
RefSeq Size 763
RefSeq ORF 405
Synonyms apoptosis-associated speck-like protein containing a CARD; ASC; ASC, TMS1, CARD5, MGC10332; CARD5; caspase recruitment domain protein 5; MGC10332; PYD and CARD domain containing; target of methylation-induced silencing-1; TMS; TMS-1; TMS1
Locus ID 29108
Cytogenetics 16p11.2
Summary This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Cytosolic DNA-sensing pathway, NOD-like receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...