Annexin IV (ANXA4) (NM_001153) Human Mass Spec Standard

Specifications

Product Data
Description	ANXA4 MS Standard C13 and N15-labeled recombinant protein (NP_001144)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203229
Predicted MW	36.1 kDa
Protein Sequence	Sequence Link (showhide) >RC203229 protein sequence Red=Cloning site Green=Tags(s) MAMATKGGTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDL KSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRISQTYQQQYGRSLED DIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHV FDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEI DMLDIRAHFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDD TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001144
RefSeq Size	2158
RefSeq ORF	963
Synonyms	ANX4; HEL-S-274; P32.5; PAP-II; PIG28; PP4-X; ZAP36
Locus ID	307
Cytogenetics	2p13.3
Summary	Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]

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