CCDC134 (NM_024821) Human Mass Spec Standard

Specifications

Product Data
Description	CCDC134 MS Standard C13 and N15-labeled recombinant protein (NP_079097)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204377
Predicted MW	26.6 kDa
Protein Sequence	Sequence Link (showhide) >RC204377 protein sequence Red=Cloning site Green=Tags(s) MDLLQFLAFLFVLLLSGMGATGTLRTSLDPSLEIYKKMFEVKRREQLLALKNLAQLNDIHQQYKILDVML KGLFKVLEDSRTVLTAADVLPDGPFPQDEKLKDAFSHVVENTAFFGDVVLRFPRIVHYYFDHNSNWNLLI RWGISFCNQTGVFNQGPHSPILSLMAQELGISEKDSNFQNPFKIDRTEFIPSTDPFQKALREEEKRRKKE EKRKEIRKGPRISRSQSEL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_079097
RefSeq Size	1279
RefSeq ORF	687
Locus ID	79879
Cytogenetics	22q13.2
Summary	In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function (PubMed:25125657). Enhances cytotoxic anti-tumor activity of CD8(+) T cells (PubMed:25125657). May inhibit ERK and JNK signaling activity (PubMed:18087676, PubMed:23070808). May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling (PubMed:23070808).[UniProtKB/Swiss-Prot Function]
Protein Families	Secreted Protein

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