Lactate Dehydrogenase B (LDHB) (NM_002300) Human Mass Spec Standard

CAT#: PH305074

LDHB MS Standard C13 and N15-labeled recombinant protein (NP_002291)



  View other "Lactate Dehydrogenase B" proteins (4)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description LDHB MS Standard C13 and N15-labeled recombinant protein (NP_002291)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC205074
Predicted MW 36.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002291
RefSeq Size 1336
RefSeq ORF 1002
Synonyms HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5
Locus ID 3945
Cytogenetics 12p12.1
Summary This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016]
Protein Families Druggable Genome
Protein Pathways Cysteine and methionine metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism
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