EXDL1 (EXD1) (NM_152596) Human Mass Spec Standard

CAT#: PH306223

EXD1 MS Standard C13 and N15-labeled recombinant protein (NP_689809)



  View other "EXDL1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description EXD1 MS Standard C13 and N15-labeled recombinant protein (NP_689809)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206223
Predicted MW 58.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_689809
RefSeq Size 3009
RefSeq ORF 1542
Synonyms EXDL1
Locus ID 161829
Cytogenetics 15q15.1
Summary RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity (By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease (By similarity).[UniProtKB/Swiss-Prot Function]
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