TBX21 (NM_013351) Human Mass Spec Standard

CAT#: PH307902

TBX21 MS Standard C13 and N15-labeled recombinant protein (NP_037483)



  View other "TBX21" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of T-box 21 (TBX21)
    • 100 ug

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Rabbit Polyclonal Anti-TBX21 Antibody
    • 100 ul

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Specifications

Product Data
Description TBX21 MS Standard C13 and N15-labeled recombinant protein (NP_037483)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207902
Predicted MW 58.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_037483
RefSeq Size 2589
RefSeq ORF 1605
Synonyms T-bet; T-PET; TBET; TBLYM
Locus ID 30009
Cytogenetics 17q21.32
Summary This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transcription Factors
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