BCAR3 (NM_003567) Human Mass Spec Standard

CAT#: PH307930

BCAR3 MS Standard C13 and N15-labeled recombinant protein (NP_003558)



  View other "BCAR3" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of breast cancer anti-estrogen resistance 3 (BCAR3)
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Specifications

Product Data
Description BCAR3 MS Standard C13 and N15-labeled recombinant protein (NP_003558)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207930
Predicted MW 92.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_003558
RefSeq Size 3203
RefSeq ORF 2475
Synonyms AND-34; MIG7; NSP2; SH2D3B
Locus ID 8412
Cytogenetics 1p22.1
Summary Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Protein Families Druggable Genome
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