LXR beta (NR1H2) (NM_007121) Human Mass Spec Standard

CAT#: PH308381

NR1H2 MS Standard C13 and N15-labeled recombinant protein (NP_009052)



  View other "LXR beta" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description NR1H2 MS Standard C13 and N15-labeled recombinant protein (NP_009052)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208381
Predicted MW 51.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_009052
RefSeq Size 2093
RefSeq ORF 1383
Synonyms LXR-b; LXRB; NER; NER-I; RIP15; UNR
Locus ID 7376
Cytogenetics 19q13.33
Summary The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
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