HS3ST1 (NM_005114) Human Mass Spec Standard

Specifications

Product Data
Description	HS3ST1 MS Standard C13 and N15-labeled recombinant protein (NP_005105)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC209256
Predicted MW	35.8 kDa
Protein Sequence	Sequence Link (showhide) >RC209256 protein sequence Red=Cloning site Green=Tags(s) MAALLLGAVLLVAQPQLVPSRTAELGQQELLRKAGTLQDDVRDGVAPNGSAQQLPQTIIIGVRKGGTRAL LEMLSLHPDVAAAENEVHFFDWEEHYSHGLGWYLSQMPFSWPHQLTVEKTPAYFTSPKVPERVYSMNPSI RLLLILRDPSERVLSDYTQVFYNHMQKHKPYPSIEEFLVRDGRLNVDYKALNRSLYHVHMQNWLRFFPLR HIHIVDGDRLIRDPFPEIQKVERFLKLSPQINASNFYFNKTKGFYCLRDSGRDRCLHESKGRAHPQVDPK LLNKLHEYFHEPNKKFFELVGRTFDWH TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005105
RefSeq Size	1965
RefSeq ORF	921
Synonyms	3OST; 3OST1
Locus ID	9957
Cytogenetics	4p15.33
Summary	Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It possesses both heparan sulfate glucosaminyl 3-O-sulfotransferase activity, anticoagulant heparan sulfate conversion activity, and is a rate limiting enzyme for synthesis of anticoagulant heparan. This enzyme is an intraluminal Golgi resident protein. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome
Protein Pathways	Heparan sulfate biosynthesis

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