Influenza Virus NS1A Binding Protein (IVNS1ABP) (NM_006469) Human Mass Spec Standard

CAT#: PH309701

IVNS1ABP MS Standard C13 and N15-labeled recombinant protein (NP_006460)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

Cited in 1 publication.

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经常一起买 (2)
Transient overexpression lysate of influenza virus NS1A binding protein (IVNS1ABP)
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Specifications

Product Data
Description IVNS1ABP MS Standard C13 and N15-labeled recombinant protein (NP_006460)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209701
Predicted MW 71.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_006460
RefSeq Size 4113
RefSeq ORF 1929
Synonyms ARA3; FLARA3; HSPC068; IMD70; KLHL39; ND1; NS-1; NS1-BP; NS1BP
Locus ID 10625
Cytogenetics 1q25.3
Summary Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity). Protects cells from cell death induced by actin destabilization (By similarity). Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription (PubMed:16582008). In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors (PubMed:25619834). Inhibits pre-mRNA splicing (in vitro) (PubMed:9696811).[UniProtKB/Swiss-Prot Function]
Protein Families Transcription Factors
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Citations (1)

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