MARCHF8 (NM_145021) Human Mass Spec Standard

CAT#: PH309891

MARCH8 MS Standard C13 and N15-labeled recombinant protein (NP_659458)



  View other "MARCHF8" proteins (11)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of membrane-associated ring finger (C3HC4) 8 (MARCH8), transcript variant 8
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Specifications

Product Data
Description MARCH8 MS Standard C13 and N15-labeled recombinant protein (NP_659458)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209891
Predicted MW 32.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_659458
RefSeq Size 5300
RefSeq ORF 873
Synonyms c-MIR; CMIR; MARCH-VIII; MARCH8; MIR; RNF178
Locus ID 220972
Cytogenetics 10q11.21-q11.22
Summary MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010]
Protein Families Druggable Genome, Transmembrane
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