STAT6 (NM_003153) Human Mass Spec Standard

CAT#: PH310065

STAT6 MS Standard C13 and N15-labeled recombinant protein (NP_003144)



  View other "STAT6" proteins (4)

Need it in bulk or customized?
Get a free quote

CNY 19,520.00


货期*
4周

规格
    • 10 ug

Product images

经常一起买 (2)
Transient overexpression lysate of signal transducer and activator of transcription 6, interleukin-4 induced (STAT6)
    • 100 ug

CNY 3,080.00


Rabbit Polyclonal anti-STAT6 antibody
    • 50 ug

CNY 4,628.00

Specifications

Product Data
Description STAT6 MS Standard C13 and N15-labeled recombinant protein (NP_003144)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210065
Predicted MW 94.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_003144
RefSeq Size 4031
RefSeq ORF 2541
Synonyms D12S1644; IL-4-STAT; STAT6B; STAT6C
Locus ID 6778
Cytogenetics 12q13.3
Summary The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
Protein Pathways Jak-STAT signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...