PON1 (NM_000446) Human Mass Spec Standard

CAT#: PH310356

PON1 MS Standard C13 and N15-labeled recombinant protein (NP_000437)



  View other "PON1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of paraoxonase 1 (PON1)
    • 100 ug

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PON1 mouse monoclonal antibody, clone OTI1F7 (formerly 1F7)
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Description PON1 MS Standard C13 and N15-labeled recombinant protein (NP_000437)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210356
Predicted MW 39.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000437
RefSeq Size 1769
RefSeq ORF 1065
Synonyms ESA; MVCD5; PON
Locus ID 5444
Cytogenetics 7q21.3
Summary This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7. [provided by RefSeq, Aug 2017]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Metabolic pathways
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