Casein Kinase 2 beta (CSNK2B) (NM_001320) Human Mass Spec Standard

Specifications

Product Data
Description	CSNK2B MS Standard C13 and N15-labeled recombinant protein (NP_001311)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC211299
Predicted MW	24.9 kDa
Protein Sequence	Sequence Link (showhide) >RC211299 protein sequence Red=Cloning site Green=Tags(s) MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSD LIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKC MDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSP VKTIR TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001311
RefSeq Size	1149
RefSeq ORF	645
Synonyms	CK2B; CK2N; Ckb1; Ckb2; CSK2B; G5A; POBINDS
Locus ID	1460
Cytogenetics	6p21.33
Summary	This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Protein Families	Druggable Genome
Protein Pathways	Adherens junction, Tight junction, Wnt signaling pathway

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