IL17RC (NM_153461) Human Mass Spec Standard

CAT#: PH313432

IL17RC MS Standard C13 and N15-labeled recombinant protein (NP_703191)



  View other "IL17RC" proteins (8)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of interleukin 17 receptor C (IL17RC), transcript variant 3
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Specifications

Product Data
Description IL17RC MS Standard C13 and N15-labeled recombinant protein (NP_703191)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213432
Predicted MW 83.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_703191
RefSeq Size 2691
RefSeq ORF 2373
Synonyms CANDF9; IL17-RL; IL17RL
Locus ID 84818
Cytogenetics 3p25.3-p24.1
Summary This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]
Protein Families Druggable Genome, Transmembrane
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