Macrophage Inflammatory Protein 1 beta (CCL4L2) (NM_001001435) Human Mass Spec Standard

Specifications

Product Data
Description	CCL4L1 MS Standard C13 and N15-labeled recombinant protein (NP_001001435)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC213959
Predicted MW	10.1 kDa
Protein Sequence	Sequence Link (showhide) >RC213959 protein sequence Red=Cloning site Green=Tags(s) MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTACCFSYTARKLPHNFVVDYYETSSLCSQPAVVFQTKRG KQVCADPSESWVQEYVYDLELN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001001435
RefSeq Size	674
RefSeq ORF	276
Synonyms	AT744.2; CCL4L; LAG-1; LAG1; SCYA4L
Locus ID	9560
Cytogenetics	17q12
Summary	This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this family member is similar to the chemokine (C-C motif) ligand 4 product, which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals, where most individuals have one to five copies. This gene copy contains a non-consensus splice acceptor site at the 3' terminal exon found in other highly similar gene copies, and it thus uses other alternative splice sites for the 3' terminal exon, resulting in multiple transcript variants. [provided by RefSeq, Apr 2014]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway

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