CHMP1A (NM_002768) Human Mass Spec Standard

Specifications

Product Data
Description	CHMP1A MS Standard C13 and N15-labeled recombinant protein (NP_002759)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC214991
Predicted MW	21.5 kDa
Protein Sequence	Sequence Link (showhide) >RC214991 representing NM_002768 Red=Cloning site Green=Tags(s) MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECARVYAENAIRKKNEGVNWLRMASRVD AVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLT TPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSVRSQEDQLSRRLAALRN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002759
RefSeq Size	2474
RefSeq ORF	588
Synonyms	CHMP1; PCH8; PCOLN3; PRSM1; VPS46-1; VPS46A
Locus ID	5119
Cytogenetics	16q24.3
Summary	This gene encodes a member of the CHMP/Chmp family of proteins which are involved in multivesicular body sorting of proteins to the interiors of lysosomes. The initial prediction of the protein sequence encoded by this gene suggested that the encoded protein was a metallopeptidase. The nomenclature has been updated recently to reflect the correct biological function of this encoded protein. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Protein Families	Druggable Genome, Transcription Factors

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