C14orf151 (INF2) (NM_022489) Human Mass Spec Standard

Specifications

Product Data
Description	INF2 MS Standard C13 and N15-labeled recombinant protein (NP_071934)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC216716
Predicted MW	135.4 kDa
Protein Sequence	Sequence Link (showhide) RC216716
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_071934
RefSeq Size	4725
RefSeq ORF	3747
Synonyms	C14orf151; C14orf173; CMTDIE; FSGS5; pp9484
Locus ID	64423
Cytogenetics	14q32.33
Summary	This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.[provided by RefSeq, Aug 2010]
Protein Families	Druggable Genome

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