PTP epsilon (PTPRE) (NM_130435) Human Mass Spec Standard

CAT#: PH317899

PTPRE MS Standard C13 and N15-labeled recombinant protein (NP_569119)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description PTPRE MS Standard C13 and N15-labeled recombinant protein (NP_569119)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217899
Predicted MW 74.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_569119
RefSeq Size 5002
RefSeq ORF 1926
Synonyms HPTPE; PTPE; R-PTP-EPSILON
Locus ID 5791
Cytogenetics 10q26.2
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq, Oct 2015]
Protein Families Druggable Genome, Phosphatase, Transmembrane
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