Myosin Phosphatase 2 (PPP1R12B) (NM_032104) Human Mass Spec Standard

CAT#: PH317905

PPP1R12B MS Standard C13 and N15-labeled recombinant protein (NP_115287)



  View other "Myosin Phosphatase 2" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of protein phosphatase 1, regulatory (inhibitor) subunit 12B (PPP1R12B), transcript variant 4
    • 100 ug

CNY 3,080.00


PPP1R12B Antibody - Middle region
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Description PPP1R12B MS Standard C13 and N15-labeled recombinant protein (NP_115287)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217905
Predicted MW 26.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_115287
RefSeq Size 2227
RefSeq ORF 672
Synonyms MYPT2; PP1bp55
Locus ID 4660
Cytogenetics 1q32.1
Summary Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq, Oct 2011]
Protein Families Druggable Genome
Protein Pathways Vascular smooth muscle contraction
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