MAX (NM_145113) Human Mass Spec Standard

CAT#: PH320343

MAX MS Standard C13 and N15-labeled recombinant protein (NP_660088)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description MAX MS Standard C13 and N15-labeled recombinant protein (NP_660088)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220343
Predicted MW 11.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_660088
RefSeq Size 2169
RefSeq ORF 315
Synonyms bHLHd4
Locus ID 4149
Cytogenetics 14q23.3
Summary The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways MAPK signaling pathway, Pathways in cancer, Small cell lung cancer
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