Integrin Linked Kinase (ILK) (NM_001014794) Human Mass Spec Standard

CAT#: PH320460

ILK MS Standard C13 and N15-labeled recombinant protein (NP_001014794)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description ILK MS Standard C13 and N15-labeled recombinant protein (NP_001014794)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220460
Predicted MW 51.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001014794
RefSeq Size 1797
RefSeq ORF 1356
Synonyms HEL-S-28; ILK-1; ILK-2; P59; p59ILK
Locus ID 3611
Cytogenetics 11p15.4
Summary This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Endometrial cancer, Focal adhesion, PPAR signaling pathway
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