DRP1 (DNM1L) (NM_012062) Human Mass Spec Standard

CAT#: PH321708

DNM1L MS Standard C13 and N15-labeled recombinant protein (NP_036192)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description DNM1L MS Standard C13 and N15-labeled recombinant protein (NP_036192)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221708
Predicted MW 81.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_036192
RefSeq Size 3293
RefSeq ORF 2208
Synonyms DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; OPA5
Locus ID 10059
Cytogenetics 12p11.21
Summary This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Protein Pathways Endocytosis, Fc gamma R-mediated phagocytosis
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