Annexin VII (ANXA7) (NM_004034) Human Mass Spec Standard

CAT#: PH321723

ANXA7 MS Standard C13 and N15-labeled recombinant protein (NP_004025)



  View other "Annexin VII" proteins (8)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
ANXA7 (Annexin VII) mouse monoclonal antibody, clone OTI1C3 (formerly 1C3)
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Specifications

Product Data
Description ANXA7 MS Standard C13 and N15-labeled recombinant protein (NP_004025)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221723
Predicted MW 52.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_004025
RefSeq Size 2176
RefSeq ORF 1464
Synonyms ANX7; SNX; SYNEXIN
Locus ID 310
Cytogenetics 10q22.2
Summary Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008]
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