beta Arrestin 1 (ARRB1) (NM_020251) Human Mass Spec Standard

CAT#: PH321737

ARRB1 MS Standard C13 and N15-labeled recombinant protein (NP_064647)



  View other "beta Arrestin 1" proteins (8)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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经常一起买 (2)
ARRB1 mouse monoclonal antibody, clone OTI2B3
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Transient overexpression lysate of arrestin, beta 1 (ARRB1), transcript variant 1
    • 100 ug

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Specifications

Product Data
Description ARRB1 MS Standard C13 and N15-labeled recombinant protein (NP_064647)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221737
Predicted MW 46.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_064647
RefSeq Size 2180
RefSeq ORF 1230
Synonyms ARB1; ARR1
Locus ID 408
Cytogenetics 11q13.4
Summary Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
Protein Families Druggable Genome
Protein Pathways Chemokine signaling pathway, Endocytosis, MAPK signaling pathway
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