beta Arrestin 1 (ARRB1) (NM_004041) Human Recombinant Protein
CAT#: TP720083
Recombinant protein of human arrestin, beta 1 (ARRB1), transcript variant 1
View other "beta Arrestin 1" proteins (8)
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CNY 3,140.00
CNY 1,999.00
CNY 3,600.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Arg418
|
Tag | C-His |
Predicted MW | 48.1 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reference Data | |
RefSeq | NP_004032 |
Locus ID | 408 |
UniProt ID | P49407, B7Z1Q3 |
Cytogenetics | 11q13.4 |
Synonyms | ARB1; ARR1 |
Summary | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011] |
Protein Families | Druggable Genome |
Protein Pathways | Chemokine signaling pathway, Endocytosis, MAPK signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC412547 | ARRB1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC418298 | ARRB1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC429613 | ARRB1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY412547 | Transient overexpression lysate of arrestin, beta 1 (ARRB1), transcript variant 2 |
CNY 3,080.00 |
|
LY418298 | Transient overexpression lysate of arrestin, beta 1 (ARRB1), transcript variant 1 |
CNY 3,080.00 |
|
PH321737 | ARRB1 MS Standard C13 and N15-labeled recombinant protein (NP_064647) |
CNY 14,250.00 |
|
TP321737 | Purified recombinant protein of Homo sapiens arrestin, beta 1 (ARRB1), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
TP762120 | Purified recombinant protein of Human arrestin, beta 1 (ARRB1), transcript variant 1,full length, with N-terminal His tag, expressed in E. coli, 50ug |
CNY 1,948.00 |
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