CD41 (ITGA2B) (NM_000419) Human Mass Spec Standard

CAT#: PH322614

ITGA2B MS Standard C13 and N15-labeled recombinant protein (NP_000410)



  View other "CD41" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) (ITGA2B)
    • 100 ug

CNY 4,840.00


Rabbit polyclonal antibody to CD41/Integrin alpha 2b (integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41))
    • 100 ul

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Specifications

Product Data
Description ITGA2B MS Standard C13 and N15-labeled recombinant protein (NP_000410)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222614
Predicted MW 113.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000410
RefSeq Size 3334
RefSeq ORF 3117
Synonyms BDPLT2; BDPLT16; CD41; CD41B; GP2B; GPIIb; GT; GT1; GTA; HPA3; PPP1R93
Locus ID 3674
Cytogenetics 17q21.31
Summary This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer
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