SAR1 (SAR1A) (NM_001142648) Human Mass Spec Standard

Specifications

Product Data
Description	SAR1A MS Standard C13 and N15-labeled recombinant protein (NP_001136120)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC226577
Predicted MW	22.4 kDa
Protein Sequence	Sequence Link (showhide) >RC226577 protein sequence Red=Cloning site Green=Tags(s) MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMT FTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMTDETISNVPILILGNKIDRTD AISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001136120
RefSeq Size	3088
RefSeq ORF	594
Synonyms	masra2; SAR1; Sara; SARA1
Locus ID	56681
Cytogenetics	10q22.1
Summary	Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).[UniProtKB/Swiss-Prot Function]

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