Collagen type II alpha 1 chain (Adult Knee Cartilage) Human Protein
CAT#: RA003
Collagen type II alpha 1 chain (Adult Knee Cartilage) human protein, 0.1 mg
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CNY 11,569.00
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规格
Cited in 1 publication. |
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Specifications
Product Data | |
Description | Collagen type II alpha 1 chain (Adult Knee Cartilage) human protein, 0.1 mg |
Species | Human |
Protein Source | Cartilage |
Concentration | lot specific |
Purity | >98% Chromatographically and immunologically pure. |
Buffer | State: Liquid (sterile filtered) purified Ig fraction. Buffer System: 0.5M Acetic Acid containing 0.01% Sodium Azide as preservative. |
Preparation | Liquid (sterile filtered) purified Ig fraction. |
Applications | Suitable for use as a control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve, for Immunoprecipitation and for Western blotting |
Protein Description | This protein has been prepared from adult human knee cartilage and is free from other collagens, human serum proteins and non-collagen extracellular matrix proteins. This product reacts with anti-Collagen Type II. Reaction with anti-Collagen I, III, IV, V or VI is negligible (typically less than 1% cross reactivity was detected by ELISA). |
Storage | Store vial at 2-8°C prior to opening. This product is stable 2-8°C as an undiluted liquid. Dilute only prior to immediate use. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001835 |
Locus ID | 1280 |
Cytogenetics | 12q13.11 |
Synonyms | ANFH; AOM; COL11A3; SEDC; STL1 |
Summary | This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008] |
Protein Pathways | ECM-receptor interaction, Focal adhesion |
Citations (1)
The use of this Proteins has been cited in the following citations: |
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Transdifferentiation of adipogenically differentiated cells into osteogenically or chondrogenically differentiated cells: Phenotype switching via dedifferentiation
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The International Journal of Biochemistry Cell Biology
,PubMed ID 24269783
[COL2A1]
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