West Nile Virus Pre-M (N-term) Human Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Concentration	lot specific
Purity	95% pure (SDS-PAGE)
Buffer	Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Phosphate buffer, pH 7.5
Preparation	Liquid purified protein
Applications	ELISA. Western blot. Lateral flow.
Protein Description	Recombinant West Nile Virus Pre-M Protein, N-terminal. N-terminal part of the Pre-M protein immunodominant region. Contains 6 histidines fusion sequence. Molecular weight approximately 20kDa. Reacts with human West Nile Virus positive serum.
Storage	Store the protein undiluted at 2-8°C for one month or (in aliquots) at -80°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
Synonyms	pre M protein antibody, West Nile virus antibody, WNVgp1 antibody, Genome polyprotein antibody
Summary	West Nile Virus is part of the flavivirus family, many of which are capable of causing serious illness in humans. The ssRNA + strand virus is enveloped and spherical with a diameter of 40-50 nm, similar to all flaviviruses. The virion of this virus is a nucleocapsid covered by a lipoprotein envelope. The envelope contains two proteins: the protein M and glycoprotein E. The nucleocapsid is a complex of protein C and mRNA. In immature particles, there are 60 icosaedrally organized trimeric spikes on the surface. Each spike consists of three heterodimers of envelope protein M precursor (prM) and envelope protein E. Inside cells, viral particles will contain a preM particle and E in a complex that matures through proteolytic cleavage and processing in the Golgi apparatus. WNV has three different effects on humans, the first is asymptomatic infection; the second is a mild febrile syndrome termed West Nile Fever; the third is a neuroinvasive disease termed West Nile meningitis or encephalitis. In infected individuals the ratio between the three states is roughly 110:30:1. The main route of human infection is through the bite of an infected mosquito.
Protein Families	ELISA. Western blot. Lateral flow.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.