Cofilin-1 (1-166, His-tag) Human Protein
CAT#: AR09012PU-N
Cofilin-1 (1-166, His-tag) human recombinant protein, 0.1 mg
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CNY 9,910.00
货期*
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规格
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MASGVAVSDG VIKVFNDMKV RKSSTPEEVK KRKKAVLFCL SEDKKNIILE EGKEILVGDV GQTVDDPYAT FVKMLPDKDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKLTG IKHELQANCY EEVKDRCTLA EKLGGSAVIS LEGKPL
|
Tag | His-tag |
Predicted MW | 20 kDa |
Concentration | lot specific |
Purity | >95% >/= 95% by SDS PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris pH 8.0, 10% Glycerol |
Preparation | Liquid purified protein |
Protein Description | Recombinant human Cofilin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Note | NCBI Accession : NP _005498 |
Storage | Store (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_005498 |
Locus ID | 1072 |
UniProt ID | P23528, V9HWI5 |
Cytogenetics | 11q13.1 |
Synonyms | CFL; cofilin; HEL-S-15 |
Summary | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004] |
Protein Families | Druggable Genome |
Protein Pathways | Axon guidance, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton |
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