HSPB8 / HSP22 (1-196, His-tag) Human Protein
CAT#: AR09392PU-L
HSPB8 / HSP22 (1-196, His-tag) human recombinant protein, 0.25 mg
Need it in bulk or customized? Get a free quote |
CNY 17,930.00
货期*
详询
规格
Cited in 2 publications. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MADGQMPFSC HYPSRLRRDP FRDSPLSSRL LDDGFGMDPF PDDLTASWPD WALPRLSSAW PGTLRSGMVP RGPTATARFG VPAEGRTPPP FPGEPWKVCV NVHSFKPEEL MVKTKDGYVE VSGKHEEKQQ EGGIVSKNFT KKIQLPAEVD PVTVFASLSP EGLLIIEAPQ VPPYSTFGES SFNNELPQDS QEVTCT
|
Tag | His-tag |
Predicted MW | 23.7 kDa |
Concentration | lot specific |
Purity | >95% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 100 mM NaCl, 10% glycerol |
Preparation | Liquid purified protein |
Protein Description | Recombinant human HSPB8, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_055180 |
Locus ID | 26353 |
UniProt ID | Q9UJY1 |
Cytogenetics | 12q24.23 |
Synonyms | CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22 |
Summary | The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Protein Kinase |
Citations (2)
The use of this Proteins has been cited in the following citations: |
---|
Heat shock proteins HSPB8 and DNAJC5B have HCV antiviral activity
,null,
PLoS ONE
,PubMed ID 29182667
[HSPB8]
|
Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3)
,null,
Cell Stress & Chaperones
,PubMed ID 20157854
[HSPB8]
|
Documents
FAQs |
SDS |
Customer
Reviews
Loading...