CDKN3 / CIP2 (1-212, His-tag) Human Protein
CAT#: AR09765PU-L
CDKN3 / CIP2 (1-212, His-tag) human recombinant protein, 0.5 mg
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CNY 17,930.00
货期*
详询
规格
Cited in 1 publication. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MKPPSSIQTS EFDSSDEEPI EDEQTPIHIS WLSLSRVNCS QFLGLCALPG CKFKDVRRNV QKDTEELKSC GIQDIFVFCT RGELSKYRVP NLLDLYQQCG IITHHHPIAD GGTPDIASCC EIMEELTTCL KNYRKTLIHC YGGLGRSCLV AACLLLYLSD TISPEQAIDS LRDLRGSGAI QTIKQYNYLH EFRDKLAAHL SSRDSQSRSV SR
|
Tag | His-tag |
Predicted MW | 25.9 kDa |
Concentration | lot specific |
Purity | >90% |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 40% glycerol, 0.1M NaCl |
Preparation | Liquid purified protein |
Protein Description | Recombinant human CDKN3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001124323 |
Locus ID | 1033 |
UniProt ID | Q16667 |
Cytogenetics | 14q22.2 |
Synonyms | CDI1; CIP2; KAP; KAP1 |
Summary | The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
Protein Families | Druggable Genome, Phosphatase |
Citations (1)
The use of this Proteins has been cited in the following citations: |
---|
The tumor suppressor CDKN3 controls mitosis
,null,
The Journal of Cell Biology
,PubMed ID 23775190
[CDKN3]
|
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