G3BP1 / G3BP (1-466, His-tag) Human Protein
CAT#: AR09781PU-L
G3BP1 / G3BP (1-466, His-tag) human recombinant protein, 0.25 mg
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CNY 17,930.00
货期*
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规格
Cited in 5 publications. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MVMEKPSPLL VGREFVRQYY TLLNQAPDML HRFYGKNSSY VHGGLDSNGK PADAVYGQKE IHRKVMSQNF TNCHTKIRHV DAHATLNDGV VVQVMGLLSN NNQALRRFMQ TFVLAPEGSV ANKFYVHNDI FRYQDEVFGG FVTEPQEESE EEVEEPEERQ QTPEVVPDDS GTFYDQAVVS NDMEEHLEEP VAEPEPDPEP EPEQEPVSEI QEEKPEPVLE ETAPEDAQKS SSPAPADIAQ TVQEDLRTFS WASVTSKNLP PSGAVPVTGI PPHVVKVPAS QPRPESKPES QIPPQRPQRD QRVREQRINI PPQRGPRPIR EAGEQGDIEP RRMVRHPDSH QLFIGNLPHE VDKSELKDFF QSYGNVVELR INSGGKLPNF GFVVFDDSEP VQKVLSNRPI MFRGEVRLNV EEKKTRAARE GDRRDNRLRG PGGPRGGLGG GMRGPPRGGM VQKPGFGVGR GLAPRQVEHH HHHH
|
Tag | His-tag |
Predicted MW | 53.2 kDa |
Concentration | lot specific |
Purity | >85% |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2 mM DTT, 100 mM NaCl |
Preparation | Liquid purified protein |
Protein Description | Recombinant human G3BP1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_005745 |
Locus ID | 10146 |
UniProt ID | Q13283, Q5U0Q1, Q6ZP53 |
Cytogenetics | 5q33.1 |
Synonyms | G3BP; HDH-VIII |
Summary | This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Citations (5)
The use of this Proteins has been cited in the following citations: |
---|
Overexpression of G3BP1 facilitates the progression of colon cancer by activating β-catenin signaling
,null,
Molecular Medicine Reports
,PubMed ID 33000280
[G3BP1]
|
A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer
,null,
iScience
,PubMed ID 32947124
[G3BP1]
|
Mammalian Orthoreovirus Factories Modulate Stress Granule Protein Localization by Interaction with G3BP1
,null,
Journal of Virology
,PubMed ID 28794026
[G3BP1]
|
G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits
,null,
The Journal of Cell Biology
,PubMed ID 27022092
[G3BP1]
|
A Pseudomonas aeruginosa Toxin that Hijacks the Host Ubiquitin Proteolytic System
,null,
PLoS Pathogens
,PubMed ID 21455491
[G3BP1]
|
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