Placenta growth factor / PGF Mouse Protein

Specifications

Product Data
Species	Mouse
Expression Host	Insect
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) ALSAGNNSTE VEVVPFNEVW GRSYCRPMEK LVYILDEYPD EVSHIFSPSC VLLSRCSGCC GDEGLHCVPI KTANITMQIL KIPPNRDPHF YVEMTFSQDV LCECRPILET TKAERRKTKG KRKRSRNQTE EPHP
Predicted MW	~ kDa
Purity	>95% by SDS-PAGE and silver stain
Buffer	Presentation State: Purified State: Lyophilized protein Buffer System: 25 mM Tris, 75 mM NaCl pH 8.5 Stabilizer: BSA
Preparation	Lyophilized protein
Protein Description	Mouse recombinant Placenta Growth Factor, aa. 135 / 132 Result by N-terminal sequencing: ALSAGNNSTE and AGNNSTE
Note	There are two equal forms, (i) Ala24 to Pro158 and (ii) Ala27 to Pro158. Protein RefSeq: NP_032853 mRNA RefSeq: NM_008827
Storage	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Bioactivity	Biological: Measured by its ability to bind to immobilized rh-sFlt-1 in a functional ELISA. Recombinant mouse PlGF can bind to immobilized rh-sFlt-1 (100 ng/well) with a linear range at 0.5-10 ng/ml.
Endotoxin	< 0.1 ng per μg of PIGF
Reference Data
RefSeq	NP_001258634
Locus ID	18654
UniProt ID	Q544A5
Cytogenetics	12 39.58 cM
Synonyms	PGFL, PLGF, PlGF
Summary	Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Also promotes cell tumor growth (By similarity).[UniProtKB/Swiss-Prot Function]

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