Dermcidin, DCD-1L Human Protein
CNY 3,560.00
货期*
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规格
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Specifications
Product Data | |
Species | Human |
Expression cDNA Clone or AA Sequence |
SSLLEKGLDG AKKAVGGLGK LGKDAVEDLE SVGKGAVHDV KDVLDSVL (1-Letter code).
|
Predicted MW | 4818.5 Da |
Purity | >95% by HPLC, Reverse phase high performance liquid chromatography analysis, Electrospray ionisation mass spectrometry analysis. |
Buffer | State: Purified peptide |
Preparation | Purified peptide |
Protein Description | Dermcidin, DCD-1L |
Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Reference Data | |
RefSeq | NP_001287783 |
Locus ID | 117159 |
UniProt ID | P81605 |
Cytogenetics | 12q13.2 |
Synonyms | AIDD; DCD-1; DSEP; HCAP; PIF |
Summary | This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014] |
Protein Families | Secreted Protein |
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