KLK5 / Kallikrein-5 (67-293, His-tag) Human Protein
CAT#: AR50450PU-N
KLK5 / Kallikrein-5 (67-293, His-tag) human protein, 0.1 mg
Size: 20 ug
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CNY 14,920.00
货期*
详询
规格
Cited in 4 publications. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MGSHMIINGS DCDMHTQPWQ AALLLRPNQL YCGAVLVHPQ WLLTAAHCRK KVFRVRLGHY SLSPVYESGQ QMFQGVKSIP HPGYSHPGHS NDLMLIKLNR RIRPTKDVRP INVSSHCPSA GTKCLVSGWG TTKSPQVHFP KVLQCLNISV LSQKRCEDAY PRQIDDTMFC AGDKAGRDSC QGDSGGPVVC NGSLQGLVSW GDYPCARPNR PGVYTNLCKF TKWIQETIQA NS
|
Tag | His-tag |
Predicted MW | 27.8 kDa |
Concentration | lot specific |
Purity | >90% by SDS - PAGE |
Buffer | Presentation State: This purified protein is available in a denatured form, making it less suitable for functional studies. Denatured proteins are better suited for applications like Western Blot (WB) or imaging assays. State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 2M Urea, 20% glycerol |
Preparation | Liquid purified protein |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001070959 |
Locus ID | 25818 |
UniProt ID | Q9Y337 |
Cytogenetics | 19q13.41 |
Synonyms | Kallikrein-Like Protein 2, KLK-5, SCTE, KLK-L2 |
Summary | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Protease, Secreted Protein, Transmembrane |
Citations (4)
The use of this Proteins has been cited in the following citations: |
---|
SOX Transcription Factors in Endothelial Differentiation and Endothelial-Mesenchymal Transitions
,null,
Frontiers in Cardiovascular Medicine
,PubMed ID 30984768
[KLK5]
|
Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice
,null,
PLoS ONE
,PubMed ID 27936229
[KLK5]
|
Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation
,null,
Cell Death & Disease
,PubMed ID 24743736
[KLK5]
|
Kallikrein-5 Promotes Cleavage of Desmoglein-1 and Loss of Cell-Cell Cohesion in Oral Squamous Cell Carcinoma *
,null,
The Journal of Biological Chemistry
,PubMed ID 21163944
[KLK5]
|
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